Vetenskapliga publikationer (80)

The Swedish Neonatal Quality Register (SNQ) - contents, completeness and validity.

Mikael Norman, Karin Källén, Erik Wahlström, Stellan Håkansson & the SNQ Collaboration.

Acta Paediatr. 2019 Apr 21. doi: 10.1111/apa.14823. [Epub ahead of print]

Association between year of birth and one-year survival among extremely preterm infants in Sweden, 2004-2007 and 2014-2016

Norman M, Hallberg B, Abrahamsson T, Björklund LJ, Domellöf M, Farooqi A, Foyn Bruun C, Gadsbøll C, Hellström Westas L, Ingemansson F, Källén K, Ley D, Maršál K, Normann E, Serenius F, Stephansson O, Stigson L, Um-Bergström P, Håkansson, S.

JAMA. 2019;321(12):1188-1199. doi:10.1001/jama.2019.2021

Rates of Extreme Neonatal Hyperbilirubinemia and Kernicterus in Children and Adherence to National Guidelines for Screening, Diagnosis, and Treatment in Sweden

Alkén J, Håkansson S, Ekéus C, Gustafsson P, Norman M

JAMA Network Open 2019;2(3):e190858. doi:10.1001/jamanetworkopen.2019.0858

Use of Concentrated Parenteral Nutrition Solutions Is Associated With Improved Nutrient Intakes and Postnatal Growth in Very Low-Birth-Weight Infants.

Späth C, Zamir I, Sjöström ES, Domellöf M.

J Parenter Enteral Nutr. 2019 Feb 12. doi: 10.1002/jpen.1522. [Epub ahead of print]

Prevalence of Severe Visual Disability Among Preterm Children with Retinopathy of Prematurity and Association With Adherence to Best Practice Guidelines.

Norman M, Hellström A, Hallberg B, Wallin A, Gustafson P, Tornqvist K, Håkansson S, Holmström G.

JAMA Network Open Jan 4, 2019, 2(1): e186801, doi:10.1001/jamanetworkopen.2018.6801.

Neonatal outcomes of very preterm or very low birth weight triplets

Shah, PS, Kusuda S, Håkansson S, Reichman B, Lui K, Lehtonen L, Modi N, Vento M, Adams M, Rusconi F, Norman M, Darlow BA, Lodha A, Yang J, Bassler D, Helenius KK, Isayama T, Lee SK

Pediatrics 2018;142:e20181938

Low Diversity of Human Milk Oligosaccharides is Associated with Necrotising Enterocolitis in Extremely Low Birth Weight Infants.

Wejryd E, Martí M, Marchini G, Werme A, Jonsson B, Landberg E, Abrahamsson TR.

Nutrients. 2018 Oct20;10(10). pii: E1556. doi: 10.3390/nu10101556.

The Swedish Approach to Management of Extreme Prematurity at the Borderline of Viability: A Historical and Ethical Perspective.

Domellöf M, Jonsson B.

Pediatrics. 2018 Sep;142(Suppl 1):S533-S538. doi: 10.1542/peds.2018-0478C.

Variations in Oxygen Saturation Targeting, and Retinopathy of Prematurity Screening and Treatment Criteria in Neonatal Intensive Care Units: An International Survey.

Darlow BA, Vento M, Beltempo M, Lehtonen L, Håkansson S, Reichman B, Helenius K, Sjörs G, Sigali E, Lee S, Noguchi A, Morisaki N, Kusuda S, Bassler D, San Feliciano L, Adams M, Isayama T, Shah PS, Lui K;

Neonatology. 2018;114(4):323-331. doi: 10.1159/000490372. Epub 2018 Aug 8.

Association of maternal diabetes with neonatal outcomes of very pretem and very low-birth-weight infants: an international cohort study.

Persson M, Shah PS, Rosconi F, Reichman B, Modi N, Kusoda S, Lehtonen L, Håkansson S, Yang J, Isayama T, Beltempo M, Lee S, Norman M.

JAMA Pediatrics. 2018 Sep 1;172(9):867-875. doi: 10.1001/jamapediatrics.2018.1811.

Respiratory Management of Extremely Preterm Infants: An International Survey.

Beltempo M, Isayama T, Vento M, Lui K, Kusuda S, Lehtonen L, Sjörs G, Håkansson S, Adams M, Noguchi A, Reichman B, Darlow BA, Morisaki N, Bassler D, Pratesi S, Lee SK, Lodha A, Modi N, Helenius K, Shah PS

Neonatology 2018;114:28-36.

The Preterm Heart in Childhood: Left Ventricular Structure, Geometry, and Function Assessed by Echocardiography in 6-Year-Old Survivors of Periviable Births.

Mohlkert LA, Hallberg J, Broberg O, Rydberg A, Halvorsen CP, Liuba P, Fellman V, Domellöf M, Sjöberg G, Norman M.

J Am Heart Assoc. 2018 Jan 20;7(2). pii: e007742. doi: 10.1161/JAHA.117.007742.

Extreme prematurity, treated retinopathy, bronchpulmonary dysplasia and cerebral palsy are significant risk factors for ophtalmologic abnormalities at 6.5 years of age.

Hellström A, Källén K, Carlssson B, Holmström G, Jakobsson P, Lundgren P, Serenius F, Stjernqvist K, Tornqvist K, Hellgren K

Acta Paediatrica 2018;107:811-821.

Cerebral palsy in extremely preterm infants

Hafström M, Källén K, Serenius F, Marsal K, Rehn E, Drake H, Ådén U, Farooqi A, Thorngren-Jerneck K, Strömberg B

Pediatrics 2018;141:e20171433

Survival in Very Preterm Infants: An International Comparison of 10 National Neonatal Networks.

Helenius K, Sjörs G, Shah PS, Modi N, Reichman B, Morisaki N, Kusuda S, Lui K, Darlow BA, Bassler D, Håkansson S, Adams M, Vento M, Rusconi F, Isayama T, Lee SK, Lehtonen L; In-ternational Network for Evaluating Outcomes (iNeo) of Neonates.

Pediatrics. 2017 Nov 21. pii: e20171264. doi: 10.1542/peds.2017-1264.

Lung function after extremely preterm birth—A population-based cohort study (EXPRESS).

Thunqvist P, Tufvesson E, Bjermer L, Winberg A, Fellman V, Domellöf M, Melén E, Norman M, Hallberg J.

Pediatric Pulmonology 2018;53:64-72.

Perinatal Outcomes After Treatment With ADHD Medication During Pregnancy.

Nörby U, Winbladh B, Källén K.

Pediatrics. 2017 Nov 10. pii: e20170747. doi: 10.1542/peds.2017-0747.

Intracranial hemorrhages in neonates born from 32 weeks of gestation-low frequency of associated fetal and neonatal alloimmune thrombocytopenia: a register-based study.

Refsum E, Håkansson S, Mörtberg A, Wikman A, Westgren M.

Transfusion. 2018;58:223-231.

Increased frequency of retinopathy of prematurity over the last decade and significant regional differences.

Holmström G, Tornqvist K, Al-Hawasi A, Nilsson Å, Wallin A, Hellström A.

JAMA Ophthalmol. 2017;135:854-861.

Reduced incidence of neonatal early-onset group B streptococcal infection after prom-ulgation of guidelines for risk-based intrapartum antibiotic prophylaxis in Sweden: analysis of a national population-based cohort.

Håkansson S, Lilja M, Jacobsson B, Källén K.

Acta Obstet Gynecol Scand. 2017 Aug 19. doi:10.1111/aogs.13211.

Blood pressure in 6-year-old children born extremely preterm

AK Edstedt Bonamy, LA Mohlkert, J Hallberg, P Liuba, V Fellman, M Domellöf, M Norman

J American Heart Association 2017 Aug 1;6(8). pii: e005858. doi: 10.1161/JAHA.117.005858

Comparing very low birth weight versus very low gestation cohort methods for out-come analysis of high risk preterm infants.

Lui K; Australian and New Zealand Neonatal Network; Canadian Neonatal Network; Swedish Neonatal Quality Register.

BMC Pediatr. 2017 Jul 14;17(1):166. doi: 10.1186/s12887-017-0921-x.

Reduction of Rod and Cone Function in 6.5-Year-Old Children Born Extremely Preterm.

Molnar AEC, Andréasson SO, Larsson EKB, Åkerblom HM, Holmström GE.

JAMA Ophthalmol. 2017;135:854-861.

Riktlinjer vid hotande förtidsbörd ska ge bättre och mer jämlik vård. Konsensusdoku-ment för enhetligt omhändertagande av gravida och extremt för tidigt födda barn.

Domellöf M, Pettersson K.

Läkartidningen 2017;114:772-4

Perinatal health services organization for preterm births: a multinational comparison

Kelly LE, Shah PS, Håkansson S, Kusuda S, Adams M, Lee SK, Sjörs G, Vento M, Rusconi F, Lehtonen L, Reichman B, Darlow BA, Lui, Feliciano LS, Gagliardi L, Bassler D, Modi N.

J Perinatol. 2017 Apr 6. doi: 10.1038/jp.2017.45. [Epub ahead of print]

Antenatal corticosteroid administration-to-birth interval and survival in extremely pre-term infants

Norberg H, Kowalski J, Marsal K, Norman M.

BJOG. 2017 Mar 15. doi: 10.1111/1471-0528.14545. [Epub ahead of print]

International variations and trends in the treatment for retinopathy of prematurity

Darlow BA, Lui K, Kusuda S, Reichman B, Håkansson S, Bassler D, Modi N, Lee SK, Lehto-nen L, Vento M, Isayama T, Sjörs G, Helenius KK, Adams M, Rusconi F, Morisaki N, Shah PS; International Network for Evaluating Outcomes of Neonates.

Br J Ophthalmol. 2017 Mar 7. pii: bjophthalmol-2016-310041. doi: 10.1136/bjophthalmol-2016-310041. [Epub ahead of print]

Case mix adjusted variation in cesarean section rate in Sweden.

Mesterton J, Ladfors L, Ekenberg Abreu A, Lindgren P, Saltvedt S, Weichselbraun M, Amer-Wåhlin I.

Acta Obstet Gynecol Scand 2017;96:597.

Preterm arteries in childhood: dimensions, intima-media thickness and elasticity of the aorta, coronaries and carotids in 6-year-old children born extremely preterm

Mohlkert LA, Broberg O, Hellström M, Pegelow-Halvorsen C, Hallberg J, Sjöberg G, Edstedt Bonamy AK, Liuba P, Fellman V, Domellöf M, Norman M.

Pediatric Research 2017 Feb;81(2):299-306. doi: 10.1038/pr.2016.212. Epub 2016 Oct 27

Central macular thickness in 6.5-year-old children born extremely preterm is strongly associated with gestational age even when adjusted for risk factors.

Molnar AEC, Rosén RM, Nilsson M, Larsson EKB, Holmström GE, Hellgren KM.

Retina. 2017 Dec;37(12):2281-2288.

Changes in the prevalence of breast feeding in preterm infants discharged from neona-tal units: a register study over 10 years.

Ericson, J. , Flacking, R. , Hellström-Westas, L. & Eriksson, M.

BMJ Open. 2016;6:e012900

Neonatal Morbidity After Maternal Use of Antidepressant Drugs During Pregnancy

Nörby U, Forsberg L, Wide K, Sjörs G, Winbladh B, Källén K.

Pediatrics. 2016 Nov;138(5). pii: e20160181.

Sodium supply influences plasma sodium concentration and the risks of hyper- and hy-ponatremia in extremely preterm infants.

Späth C, Sjöström ES, Ahlsson F, Ågren J, Domellöf M.

Pediatr Res. 2017;81:455-460.

Durations of second stage of labor and pushing, and adverse neonatal outcomes: a population-based cohort study

Sandström A, Altman M, Cnattingius S, Johansson S, Ahlberg M, Stephansson O.

J Perinatol. 2017 Mar;37(3):236-242. doi: 10.1038/jp.2016.214. Epub 2016 Dec 8.

Scoping review shows wide variation in the definitions of bronchopulmonary dysplasia in preterm infants and calls for a consensus.

Hines D, Modi N, Lee SK, et al. International Network for Evaluating Outcomes (iNeo) of Neo-nates.

Acta Paediatr. 2017;106:366-74.

Aggressive posterior retinopathy of prematurity is associated with multiple infectious episodes and thrombocytopenia.

Lundgren P, Lundberg L, Hellgren G, Holmström G, Hård AL, Smith LE, Wallin A, Hallberg B, Hellström A.

Neonatology. 2017;111:79-85.

Hypertensive disorders of pregnancy and outcomes of preterm infants of 24 to 28 weeks' gestation.

Gemmell L, Martin L, Murphy KE, Modi N, Håkansson S, Reichman B, Lui K, Kusuda S, Sjörs G, Mirea L, Darlow BA, Mori R, Lee SK, Shah PS.

J Perinatol. 2016 Dec;36(12):1067-1072. doi: 10.1038/jp.2016.133. Epub 2016 Sep 1.

Extremely Preterm Infants in Sweden Study Group. Neurodevelopmental Outcomes Among Extremely Preterm Infants 6.5 Years After Active Perinatal Care in Sweden.

Serenius F, Ewald U, Farooqi A, et al.

JAMA Pediatr. 2016;170:954-963.

Screening for retinopathy of prematurity can be started in postmenstrual week 31 in very premature babies!

Holmström G, Hellström A, Jakobsson P, et al.

Eye (Lond). 2016;30:1524-1525.

Case mix adjustment of health outcomes, resource use and process indicators in childbirth care: a register-based study.

Mesterton J, Lindgren P, Ekenberg Abreu A, et al.

BMC Pregnancy Childbirth. 2016;16:125

Neonatal Outcomes of Very Low Birth Weight and Very Preterm Neonates: An International Comparison.

Shah PS, Lui K, Sjörs G, et al. International Network for Evaluating Outcomes (iNeo) of Neonates.

J Pediatr. 2016;177:144-152.

Country-Specific vs. Common Birthweight-for-Gestational Age References to Identify Small for Gestational Age Infants Born at 24-28 weeks: An International Study.

Martin LJ, Sjörs G, Reichman B, et al. International Network for Evaluating Outcomes (iNeo) of Neonates Investigators.

Paediatr Perinat Epidemiol. 2016;30:450-61.

Ophthalmologic Outcome of Extremely Preterm Infants at 6.5 Years of Age: Extremely Preterm Infants in Sweden Study (EXPRESS).

Hellgren KM, Tornqvist K, Jakobsson PG, et al.

JAMA Ophthalmol. 2016;[Epub ahead of print].

Five years of treatment for retinopathy of prematurity in Sweden: results from SWEDROP, a national quality register.

Holmström G, Hellström A, Jakobsson P, et al.

Br J Ophthalmol. 2016;100:1656-1661.

Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks.

Elden H, Hagberg H, Wessberg A, Sengpiel V, Herbst A, Bullarbo M, Bergh C, Bolin K, Malbasic S, Saltvedt S, Stephansson O, Wikström AK, Ladfors L, Wennerholm UB

BMC Pregnancy Childbirth. 2016 Mar 7;16:49. doi: 10.1186/s12884-016-0836-9.

Intakes of Micronutrients are Associated with Early Growth in Extremely Preterm Infants - A Population-Based Study.

Sjöström ES, Öhlund I, Ahlsson F, Domellöf M.

J Pediatr Gastroenterol Nutr. 2016;62:885-92.

Impact of obstetric factors on outcome of extremely preterm births in Sweden: prospective population-based observational study (EXPRESS).

Källén K, Serenius F, Westgren M, et al.

Acta Obstet Gynecol Scand. 2015;94:1203-14.

Sepsis as a risk factor for neonatal morbidity in extremely preterm infants.

Ohlin A, Björkman L, Serenius F, et al.

Acta Paediatr. 2015;104:1070-6.

Association between cereberal palsy and microscopically verified placental infarction in extremely preterm infants.

Vinnars MT, Vollmer B, Nasiell J, et al.

Acta Obstet Gynecol Scand 2015;94:976-82.

Intensity of perinatal care for extremely preterm infants: outcomes at 2.5 years.

Serenius F, Blennow M, Maršál K, et al.

Pediatrics. 2015;135:e1163-72.

Placental pathology in relation to stillbirth and neonatal outcome in an extremely preterm population: a prospective cohort study.

Vinnars MT, Papadogiannakis N, Nasiell J, et al.

Acta Obstet Gynecol Scand. 2015;94:584-90.

Low energy intake during the first 4 weeks of life increases the risk for severe retinopathy of prematurity in extremely preterm infants.

Stoltz Sjöström E, Lundgren P, Öhlund I, et al.

Arch Dis Child Fetal Neonatal Ed. 2015;101:F108-13.

Timing of pharmacological treatment for patent ductus arteriosus and risk of secondary surgery, death or bronchopulmonary dysplasia: a population-based cohort study of extremely preterm infants

Gudmundsdottir A, Johansson S, Hakansson S, Norman M, Kallen K, Bonamy Ak.

Neonatology 2015 107;2 87-92. doi:10.1159/000367887

Intake and macronutrient content of human milk given to extremely preterm infants.

Stoltz Sjöström E, Öhlund I, Tornevi A, Domellöf M.

J Hum Lact 2014;30:442-9.

Evaluation of new guidelines for ROP screening in Sweden using SWEDROP – a national quality register.

Holmström G, Hellström A, Jakobsson P, et al.

Acta Ophthalmol. 2015;93:265-8.

The time for a confirmative necrotizing enterocolitis probiotics prevention trial in the extremely low birth weight infant in North America is now!

Abrahamsson TR, Rautava S, Moore AM, Neu J, Sherman PM.

J Pediatr. 2014 Aug;165(2):389-94. doi: 10.1016

The international network for evaluating outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care.

Shah PS, Lee SK, Lui K et al.

BMC Pediatr 2014;14:110-121.

Ophthalmologic outcome at 30 months' corrected age of a prospective Swedish cohort of children born before 27 weeks of gestation: the extremely preterm infants in Sweden study.

Holmström GE, Källen K, Hellström A, et al.

JAMA Ophthalmol 2014;132:182-9.

Association between placental pathology and neonatal outcome in preeclampsia: a large cohort study

Vinnars Mt, Nasiell J, Holmstrom G, Norman M, Westgren M, Papadogiannakis N

Hypertension in pregnancy 2014 33;2 145-58. doi:10.3109/10641955.2013.842584

Perioperative nutrition in extremely preterm infants undergoing surgical treatment for patent ductus arteriosus is suboptimal.

Westin V, Stoltz Sjöström E, Ahlsson F et al.

Acta Peadiatr 2014;103:282-288.

The role of coagulase-negative staphylococci in early onset sepsis in a large European cohort of very low birth weight infants.

Mularoni A, Madrid M, Azpeitia A, et al.

Pediatr Infect Dis J. 2014;33:e121-5.

EXPRESS study shows significant regional differences in 1-year outcome of extremely preterm infants in Sweden.

Serenius F, Sjörs G, Blennow M, et al.

Acta Paediatr 2014;103:27-37.

Prenatal inflammatory risk factors for development of bronchopulmonary dysplasia.

Eriksson L, Haglund B, Odlind V, et al.

Pediatr Pulmonol. 2014;49:665-72.

Nutrient intakes independently affect growth in extremely preterm infants: results from a population-based study

Stoltz Sjöström E, Öhlund I, Ahlsson F, et al.

Acta Paediatr. 2013;102:1067-74.

Regional differences in screening for retinopathy of prematurity in infants born before 27 weeks of gestation in Sweden - the EXPRESS study.

Austeng D, Källen K, Hellström A, et al.

Acta Ophthalmol. 2014;92;311-5.

Neurodevelopmental outcome in extremely preterm infants at 2.5 years after active perinatal care in Sweden.

Serenius F, Källén K, Blennow M, et al.

JAMA. 2013;309:1810-20.

Swedish National Register for Retinopathy of Prematurity (SWEDROP) and the Evaluation of Screening in Sweden.

Holmstrom G, Hellstrom A, Jakobsson P, et al.

Arch Ophtalmol. 2012;130:1418-24.

Early Skin-to-Skin Care in Extremely Preterm Infants: Thermal Balance and Care Environment.

J Karlsson V, Heinemann AB, Sjörs G, et al.


Screening for retinopathy of prematurity in infants born before 27 weeks of gestation in Sweden.

Austeng D, Källén K, Hellström A, et al.

Arch Ophthalmol. 2011; 129:167-72.

Effects on neonatal morbidity and mortality after regional change in management of post term pregnancy.

Grunewald C, Saltvedt S, Håkansson S, Källén K.

Acta Obstet Gynecol Scand 2011;90:26-32.

Natural history of retinopathy of prematurity in infants born before 27 weeks of gestation in Sweden.

Austeng D, Källén K, Hellström A et al.

Arch Ophtalmol 2010; 128:1289-94.

Neonatal morbidity in moderately preterm infants: a Swedish national population-based study.

Altman M, Vanpée M, Cnattingius S, Norman M.

J Pediatr. 2011;158:239-44.

Incidence of and risk factors for neonatal morbidity after active perinatal care: extremely preterm infants study in Sweden.


Acta Paediatr. 2010;99:978-92.

Treatment for retinopath of prematurity in infants born before 27 weeks of gestatio in Sweden.

Austeng D, Källén K, Ewald U, et al.

Br J Ophtalmol, 2010;94:1136-9.

Incidence of Retinopathy of Prematurity in infants born before 27 weeks’s gestation in Sweden.

Austeng D, Källén K, Ewald U, et al.

Arch Ophthalmol. 2009;127:1315-9.

One-year survival of extremely preterm infants after active perinatal care in Sweden.

Fellman V, Hellström-Westas L, Norman M, et al.

JAMA. 2009;301:2225-33.

Passive induction of hypothermia during transport of asphyxiated infants: a risk of excessive cooling.

Hallberg B, Olson L, Bartocci M, et al.

Acta Paediatrica 2009;98:942-5.

Moderately preterm infants and determinants of length of hospital stay.

Altman M, Vanpée M, Cnattingius S, Norman M.

Arch Dis Child Fetal Neonatal Ed. 2009;94:F414-418.

Neonatal antibiotic treatment is a risk factor for early wheezing.

Alm B, Erdes L, Möllborg P, et al.

Pediatrics. 2008 Apr;121(4):697-702.

Shorter hospital stay for moderately preterm infants.

Altman M, Vanpée M, Bendito A, Norman M.

Acta Paediatr 2006;95:1228-33.